Pages

选择哪一个肉毒杆菌素品牌?价格?



应该选择哪一个肉毒杆菌素品牌?

了解了肉毒杆菌素的作用,过后呢!我想,重要的就是选择肉毒杆菌素的品牌了。或许,很多人都只是以为,Botox就是肉毒杆菌素的唯一代表,其实不然。
市场上,到现今为止共有4个品牌,一个,就是Botox,也就是我们最熟悉的,熟悉到一提到肉毒杆菌素就想到Botox的地步,就像以前小时候想到牙膏就想到Colgate一样,原因是因为它是最早被正式合法启用的。

2009年前在世界上可以生产美容用肉毒素杆菌的国家只有三个:美国、英国和中国,这三个地方的生产商给了它不同的名字,在美国,它叫Botox(这是我们最熟悉的),在英国它变成了Dysport,而在中国,它是Btxa,也就是兰州衡力品牌的肉毒杆菌素。在2009年韩国也加入了这一个行列,他们把它叫做Neuronox

经过美国FDA 美國食品藥物管理局(FDA)核准的就只有BotoxDysportBtxa通过了中国卫生署的核准,在中国可以合法使用。Neuronox的出产商表示说Neuronox其实和Botox一样有效和安全,不过,也许需要更多的资料来支持这种说法,毕竟它还没有通过FDA的核准,而且也还没有足够的数据。

不过在马来西亚,有在卫生部注册的肉毒杆菌素品牌只有BotoxDysport,而其他两个Neuronox Btxa就没有在卫生部注册。

Product Detail Information for MAL19970915A
Product Information :
Product Name
:
BOTOX (BOTULINUM TOXIN TYPE A) IM INJECTION



Holder Name
:
ALLERGAN MALAYSIA SDN BHD
Address
:
NO 4A JALAN 19/1
 
:
46300
 
:
PETALING JAYA
 
:
SELANGOR
 
:
MALAYSIA



Manufacturer Name
:
ALLERGAN PHARMACEUTICALS IRELAND
Address
:
CASTLEBAR ROAD WESTPORT COUNTY MAYO
 
:
IRELAND




Ingredients Information :
No.
Substance Name
1
CLOSTRIDIUM BOTULINUM TOXIN TYPE A

Product Detail Information for MAL20000731A
Product Information :
Product Name
:
DYSPORT 500U/VIAL,POWDER FOR INJ



Holder Name
:
EMERGING PHARMA SDN. BHD.
Address
:
PHILEO DAMANSARA II 3A03, BLOCK B LOT 15, JALAN 16/11
 
:
46350
 
:
PETALING JAYA
 
:
SELANGOR
 
:
MALAYSIA



Manufacturer Name
:
IPSEN BIOPHARM LTD
Address
:
ASH ROAD,WREXHAM INDUSTRIAL ESTATE, WREXHAM,LL13 9UF,
 
:
UNITED KINGDOM




Ingredients Information :
No.
Substance Name
1
CLOSTRIDIUM BOTULINUM TOXIN TYPE A


那么,如果有兴趣想要接受肉毒杆菌素除皱治疗的话,应该选择哪一种品牌?

安全性最高的当然是经过卫生部核准的,因为它们也是经过美国FDA核准的,然后通过正式的官方管道进来马来西亚合法销售和使用的,万一有什么问题,我们直接可以向厂商咨询研讨和善后;无需关税的走私肉毒杆菌素价格虽然比较便宜,可是没有质量保证,使用起来很危险,万一有什么问题就是打落牙齿和血吞了,有苦说不出。(Pasar Malam 售卖的所谓本地肉毒杆菌素,听起来就根本不可相信了。)

个人觉得,这个治疗是注射在我们每天面对人的面容上,想要接受疗程的话就应该选择有质量保证的产品,千万不要铤而走险选择便宜而质量不受保证的产品,因为一切后果或问题都是在脸上的,要等它的效果消失,至少得等四到六个月。如果真的很想要治疗可是钱包羞涩,那么,建议是先努力存钱吧!不要拿自己的脸来开玩笑或冒险。

价格呢!

也许大家会关心这个问题,而这个也是敏感的问题。其实有两种算法,一个是算部位(part)计算,另外一个是单位(Unit)的算法。两种正式管道进入我国,然后在卫生部注册的肉毒杆菌素价格差不多一样,不过如果是走私进来无需关税的肉毒杆菌素,价格可能就会便宜许多了。

正式的价格建议还是去相关诊所咨询会比较好,这里只是说一个大概,一个部分大概是马币六百到一千多不等,通常都会计算用量多少来决定价格;有些人的肌肉比较强壮体积比较大,所需要的分量也就比较多,收费也会比较多。

在大马,绝大部分的收费都比国外的便宜,好像上次一个澳洲过来的讲师,她说在澳洲,收费是450澳币一个部位,如果是单位,就25澳币一个单位,高收入的国家,收费也不低廉。在美国,一单位的收费在10-15美金之间,因为也要看看你是在哪一个医生或哪一间诊所(地点/环境)所接受的治疗;在大马,收费相对可以说是相对廉宜,大众都可以使用。

BotoxDysport在我国算是医药用物,正版的药物只有合格注册的医生才可以买得到,最好是接受有受过严格训练的医生的注射治疗,安全性才最高。



备注:
Botox一罐有100单位,一个部位(好像额头算一个,皱眉纹算一个)大概需要20-30单位的用量。
Dysport一罐有500单位,不过它的分量大概是3.5-5单位等值Botox的一个单位,算起来是一样的。




                                                                                                               


                                                                                                              by William
Updated 20 August 2015

皱眉纹,我不要!

“你看起来好严肃。”

“最近很烦吗?”

“怎么一直愁眉苦脸的样子,你还好吗?”


如果眉头间的肌肉总是不自觉地皱在一起,那么,身边关心你的人就会担心而来关心你。



眉宇之间总是可以传递许多的信息,也可以不自觉地让别人感觉你的情绪,就好像下意识的皱眉,也许只是习惯使然,也许只是思考,紧张,焦虑的表情,也许只是 生气或发愁地情绪表达,久而久之,肌肉习惯了如此的运作,常做类似的情绪表达或动作,就会开始出现所谓的动态皱眉纹,如果没有任何治疗让肌肉放松舒展,那 么,动态皱眉纹最终将会变成静态皱眉纹。

两眉之间的皱纹,总是会让人有严肃,不友善,难以亲近的感觉,其实处理并不会很难,可是要看它的阶段和严重性。

如果只是刚刚开始酝酿的阶段,学着调适自己,减少运用皱眉的肌肉,时刻放松,那么也许皱眉纹也许没有那么快变明显。如果皱眉纹已经形成了,那么最快的治疗就是以肉毒杆菌素来让肌肉放松。如果已经是静态纹的地步了,那么除了肉毒杆菌素外,还必须加上玻尿酸注射来达到最好的效果。

让我们来看看到底是哪一条肌肉让我们皱眉的。

就是标明C和D的肌肉。

C = Corrugator , 皱眉肌

 D = Procerus , 眉间肌

皺眉肌的作用為拉下並靠攏眉毛,在額頭處產生垂直的皺紋。此肌肉所謂“皺眉肌”,因此其動作可視爲受苦、不適、悲傷、強忍痛楚的主要表現。當暴露在強光之下時,皺眉肌也會收縮,以靠攏兩邊眉毛,遮擋並減少進入眼睛光線。 (资料来源 = http://zh.wikipedia.org/wiki/%E7%9A%BA%E7%9C%89%E8%82%8C)
眉间肌的作用是辅助皱眉肌,太过活跃的话也会造成皱纹。


以下是诊所的一个案例(照片已经获得照片主角本人允许分享)


这位先生对于他紧皱的眉头有些不满,太过活跃的皱眉肌让他的眉间看起来好像有M字形的忧愁,于是,他愿意接受肉毒杆菌素的治疗,来让过度活跃的皱眉肌放松,休息。

上图是接受肉毒杆菌素治疗前,下图是接受治疗后的两个星期
两个礼拜后的复诊,可以看得出情况已经改善,不过,如果要完全没有看到皱纹的效果,需要多几次的治疗,在每隔六个月。但是,我们想要的是自然的效果,尤其是男生,如果完全把皱纹从脸上除掉的话,看起来就不会那么的自然了。

上图是接受肉毒杆菌素治疗前,下图是接受治疗的十个月后,可以看得出之前的动态皱眉纹重新开始出现,不过还是比接受治疗前的状况好的多

通常肉毒杆菌素的效果疗效是四到六个月之间,过了之后它的效果就会消失。
这个是好消息,也是坏消息。先说坏的消息,就是,如果你喜欢它的效果,六个月后就需要重新接受治疗,因为它的效果只是暂时性的,不永久。
好的消息是,它只是暂时性,并不会永久的留在你的身体或脸上,所以不必担心有任何的后遗症。到目前为止,还没有任何关于长期使用而引起的后遗症报告。所以相对来说,是安全的。

有人会担心,如果接受治疗,六个月药效消失后,皱纹是不是会更严重,也就是人家所谓的反扑效果。其实不然,肉毒杆菌素的原理是让肌肉放松,休息,那么,休息和放松的肌肉体积会慢慢的变小,从原本的XL size变成L size,再变成 M size,再变成 S size, XS size,这些变化需要很长的时间来完成,所以,如果从XL 变成 L 了,那么,如果就此停住没有继续接受治疗,肌肉就会从L size再慢慢的恢复活跃,慢慢的重新变大回复XL size。并不会立刻打回原形。

会难以了解吗?




                                                                                                              by William

Myths about Botox


     It's all about muscle


     Botolinum toxin or better known by its commercial name of Botox is generating much interest these days. Knowing that I handle quite a fair bit of Botolinum toxin in my daily work, my aunt once exclaimed, “What? You inject toxin into someone else’s face. Wouldn’t that cause the person to have toxin deposition in the body?” And well, she is not the only person to say so. There were many others friends, relatives and patients alike, who asked me the same question. I feel that it is about time people get to know this medication a little bit better.

     Botolinum toxin was first discovered in contaminated sausages in the late 1900s. What happened at that time was that people who consumed contaminated sausages had weakening of the muscle. Later, they started to discover that the weakening of muscles was actually caused by a toxin secreted by the bacteria called Clostridium botolinum and the name botolinum was coined from the word botulus which means sausage in Latin. 

     Fast forward to the present day, through modern technology, we managed to extract the components of the toxin which causes the relaxation effect to the muscle– the neurotoxin. This neurotoxin is purified and does not contain other elements that may cause harm to the body. The powerful neurotoxic effect of the toxin has found its way to benefit mankind in a multitude of ailments. Treating diseases such as cervical dystonia, a neuromuscular disorder which causes the neck to be in spasm (constant contraction of the muscle) at all times; strabismus or better known as squinting (unbalanced muscle strength of the eye muscles) and many more has been made possible with the discovery of this medication. And the indication of this medication is still growing over time. 

     In my line of work, this medication is used for face reshaping, wrinkle softening and treating tired looking eyes. The logic behind its use in the aDamaesthetic field is simple. We relax the muscles which are in constant contraction. These muscles which are overly active are “taught” to relax but not to be paralysed. The result is a person with a more “relaxed” complexion rather than one who appears “strained”.  Proper use of this medication relaxes the face without leaving a “plastinated” or expressionless facies and this can be done with proper titration of the medication. If you do not like the effect of this medication, fret not, as the effect will wear off by itself in a few months’ time.  

     Having talked about the uses of Botolinum toxin, I would like to stress that though this medication actually has its benefits and side effects as other medications. The good news is that this medication has been extensively studied to look out for its benefit and side effects before it is allowed to be marketed. Common side effects are, transient headache, blurring of vision, which will recover over time. If you are interested with the treatment, please discuss with your doctor before proceeding for treatment. 

     As you may notice, the word toxin has been replaced by medication at the end of the article. Like all other medications, proper use of this substance makes it a medication while improper use may inversely turn it into a toxin.


Anna Hoo.

Simple ways to make your eyes shines.



Simple ways to make your eyes shines.



Eyes are the most precious body parts that any person can have. They give colours to life and they are, in fact, the one of the first things that people notice when looking into a person’s face and are the best organ to express one’s emotion and mood. If you take good care of your eyes, your eyes will shines and you will appear healthy. Glowing eyes exudes confidence and vigour while a pair of weary eye only spells lifelessness.

Maintaining a pair of good looking eyes may not be an easy task. Nowadays, you can find countless number of eye care kits, cosmetics and make up. Some of these things may contain chemicals that irritate the sensitive eyes. One should exercise caution when choosing the right treatment for your eyes. And I would like to share some of my tips with you that will help make your eyes sparklingly good looking.



  1. Rest well: Like any other body parts, the eyes need rest after a long day of work. Peering into the computer monitor, looking into glaring light for long hours or simply working on small fine detailed structure do strain the eyes. The eyes need adequate rest after these strenuous activities. Simple having adequate sleep at night make wonders.  Another things you can do for those who always in front of the computer, is to close your eyes and count to 10 every half an hour of using the computer, or try to look away from the screen and focus on some faraway object, as often as possible. If you train yourself into the habit, your eyes should feel much better at the end of your working day.



  1. Protect your eyes from UV rays. It is proven that UV rays can seriously damage your eyes, but good sun glasses can prevent this damage. Please select sun glasses that can block at least 98% of the UV radiation. Malaysia is a tropical country which is sunny through out the years. Don’t forget your sun glasses when you are out under the sun, just like the skin needs sunblock, our eyes do need sunglasses.





  1. Good supplement for you and your eyes. Recent studies have shown that vitamins of the antioxidant group can prevent, or at least slow down, age-related conditions like macular degeneration and the development of cataracts. Laboratory studies have provided preliminary evidence that bilberry consumption may inhibit or reverse eye disorders such as macular degeneration. Bilberries are recognized as a good source of flavonoids which have strong antioxidative activity. You can get bilberry extract from most of the pharmacy in Malaysia. Besides bilberry, Vitamins C, A and E, folic acid, selenium and zinc are also beneficial for the health of your eyes.



  1. Good Lighting It is a common knowledge that poor lighting can cause eyestrain, but light that is too bright can do as much damage as well. The best lighting for working on the computer is ceiling light from above or alternatively a soft desk light, coming from the side. You can try decreasing the brightness of your monitor. The image won't be so stunning, but your eyes will feel much better by the end of the day.





  1. Regular Eye Check: Get an eye check up every year when you hit thirty five and above. Many eye diseases progress slowly with no symptoms at all, catching many people by surprise. When vision symptoms become obvious, some irreversible damage would have already been made. Regular tests will help to detect any eye problem early and slow down, or even stop, the progression of some diseases before any permanent harm occur.



  1. Pampering at night: After a long day, before you go to bed, you can pamper your eye by applying cucumber, or eye masks that you can easily get over the counter to return the hydration of the skin surrounding the eyes. The natural ingredients in the cucumber are eye-friendly goodness, such as fruit acid, vitamin A and C, magnesium and calcium. It is significantly known for its soothing properties helping to relax your eyes and reduce redness of your eyes. Eye mask that contain hyaluronic acid, vit c, rose extract will have help to revive the skin as well.



Next will let you know how to select skin care for your eyes...




 by
Anna Hoo

肉毒杆菌素的除皱原理

来说一说肉毒杆菌素的除皱原理。

简单的来说,肉毒杆菌素的注射可以阻断“神经”与“肌肉”之间的神经冲动,进而让过度收缩的肌肉松弛,使动态性皱纹减少,或完全消失。

从医学角度来看,肌肉之所以能够收缩,乃是依赖在神经线末端分泌出的化学物质:乙醯胆碱(Acetyl choline)。肉毒杆菌毒素注入人体后能够紧密地附着在神经末稍,并且抑制乙醯胆碱的正常释放,使得肌肉收不到神经讯号,而无法正常收缩,进而产生 「暂时性」地力量减弱或麻痹。

另外,乙醯胆碱也是让皮下层汗线排汗的讯号,所以肉毒杆菌毒素除了能够除皱外,亦能够减少汗水过度分泌。

治疗后的脸部肌肉可以保持平滑而且不会形成皱纹,而未接受治疗的肌肉仍然可以正常的收缩,因此不会影响正常的脸部表情。

可是,注射肉毒杆菌素也要看看是不是有经验的医生的技术:
  1. 对的肌肉,万一这个“肌肉安眠剂”不小心让不应该休息睡觉的肌肉休息睡觉的话,那么,治疗后的脸就会看起来怪怪的。
  2. 还有另外一个就是肉毒杆菌素的分量,分量过少可能皱纹不能够完整的清除掉;分量过多,整个肌肉都“麻痹”动弹不得,就会给人一种看起来僵硬的不自然表情;足够的分量就可以刚刚好的去除动态皱纹,然后又可以保持自然的表情,人家看了只会觉得“哦!怎么看起来好像年轻了?”而不是“哈!你去打了肉毒杆菌素,所以看起来僵僵的。”

不过,这些都是可以调整的,通常在治疗后的一两个星期,有经验的医生都会要求你复诊,看看接受肉毒杆菌素治疗后的表情到底自然不自然,是不是需要一些微微的调整?每一个人的体质都不一样,肌肉的强度也不一样,不能够只靠着书上写的标准分量,标准注射地点,就可以打遍所有人的脸而效果自然,美观,对称。大部分的人的脸都会有些些微的差异,一边会比较大,或一边的脸上的肌肉会比较活跃,所以如果接受肉毒杆菌素的治疗的话,有经验的医生就会调整两边的分量,就好像比较活跃强壮的肌肉就需要比较多的分量,我们所想要的效果,就是自然和对称的脸孔,和皱纹减少。

以前的年代,要除去脸上的皱纹,可能必须借助拉皮,所以一般的人们通常都会在上了年纪,皱纹比较深的时候才作拉皮手术,在皱纹刚刚出现冒头的时候,则无计可施。肉毒杆菌素的出现可以说是打救了这段时期,所以一些年轻人如果对自己的动态皱纹有意见的话,也极适用。

现在这个时代,有人就说,所有的女生都需要肉毒杆菌素,因为皱纹是女人的天敌,而肉毒杆菌素就是对付皱纹最厉害的武器,这个说法行的通吗?呵呵!





By William Hoo

关于肉毒杆菌素

要清楚,肉毒杆菌,和肉毒杆菌素是有很大的分别的。

首先,让我们来了解,什么是肉毒桿菌

它是一种细菌,Clostridium botulinum)一种厌氧菌,当环境不适合生长时,它可产生一种耐高温、耐干旱、耐化学药剂的内孢子。

人们通常对肉毒杆菌的认识,就是从报章上时不时看到的新闻,在某某地方有人误食用了含有肉毒杆菌的食物而引起的中毒事件,从而认为肉毒杆菌是一个很危险的东西。是的,肉毒杆菌是引起食物中毒的主要原因之一,也是一个很危险的东西。误食这类罐头食品会令人产生视线模糊,上吐下泻,全身无力等中毒现象。

它最常见于密封的罐头食品、香肠、火腿、熏鱼等肉类加工品,由于肉毒杆菌在缺氧的环境中,会制造气体,因此在生活中只要看到膨胀的罐头,千万不可冒然打开食用,以免中肉毒杆菌的毒。

目前已知有肉毒杆菌ABCDEFG等七型,其中食物中毒最常见的是ABE三型。




肉毒杆菌素,并不是肉毒杆菌,它只是一种蛋白质,一种由肉毒杆菌分泌产生的蛋白质。

到目前为止,一共有多达7种不同的肉毒杆菌素亚型被分离出来,分别称为ABC1DEF、以及 G 型,它们都可以有共同的作用,在神经肌肉交触处,阻断乙醯胆鹼释放的能力,进而断绝神经讯号的传递。

1970年代之后,经过医学界的不断研究试验,肉毒杆菌素开始运用在眼瞼痙攣、半面痙攣、斜視、小兒腦性麻痺、斜頸症等的治疗。在医学上的肉毒杆菌素注射剂量十分微小,远小于中毒的剂量,所以对人体可以说是不会造成任何伤害。

而肉毒杆菌素在医学美容的发现,是一个十分美丽的意外。在1980年代,有眼科医生在运用肉毒杆菌素治疗眼瞼痙攣时,意外的发现,在注射肉毒杆菌素附近的皮肤,皱纹减少了。从此后,肉毒杆菌素从“黑名”翻成“红名”,成为微调界最重要的成员之一。在1989年,美国FDA核准,肉毒杆菌素正式成为临床治疗药物。

 美容方面使用的肉毒桿菌素是一种天然、纯化的蛋白質,從細菌的分泌物质经过高科技纯化萃取而產生。主要成分為高度纯化的A型肉毒桿菌素。可以阻断神经的传导,用來治疗過度活跃的肌肉,可让造成皱纹的肌肉放松,变成一個平滑、年轻且更有青春活力的容颜。



by William Hoo